Key-Obs Preclinical CRO Specialized In CNS, Behavioral Neuroscience And Neuroinflammation Studies

Key-Obs is an independent preclinical contract research organization located in France delivering high-value CNS pharmacology data for pharmaceutical and biotechnology companies developing innovative therapies for brain and psychiatric disorders. Our teams design, run and analyze in vivo studies in rodents using translational and validated models to support proof-of-concept, dose selection, and mechanism-of-action questions. By working with Key-Obs, sponsors benefit from a partner that understands neurodegenerative diseases, neurodevelopmental disorders and neuroinflammation pathways and can adapt protocols to your compound and target.

Comprehensive CNS-Focused Preclinical Services

Through its service portfolio described on https://www.key-obs.com/services.php, Key-Obs provides a complete range of CNS preclinical services including behavioral assessment, pharmacology efficacy studies, cognitive testing, anxiety and depression models, as well as models for autism spectrum disorders and Alzheimer’s disease. Each study is conducted under strict quality requirements to generate robust, reproducible and decision-making data that sponsors can integrate in their R&D packages. Our scientists help you select the most relevant in vivo model based on indication, age, strain and read-outs, ensuring that your CNS asset moves forward faster.

Behavioral And Pharmacology Tests For Translational CNS Research

On the dedicated page https://www.key-obs.com/tests.php you can find the list of behavioral neuroscience tests routinely performed at Key-Obs: locomotor activity, social interaction, memory and learning tests, anxiety-like behavior, depression-like behavior, sensorimotor gating and other endpoints relevant to psychiatric disease models. These tests are combined with pharmacology studies to evaluate efficacy of new chemical entities, biologics or repositioned drugs. When needed, biomarker sampling and imaging can be integrated to strengthen the translational value of the data and to reflect expected clinical outcomes.

Expertise In Neuro-Inflammation And Neurodegenerative Diseases

Key-Obs also proposes a specialized offer in neuroinflammation for CNS and brain disorders, presented on https://www.key-obs.com/neuro-inflammation.php. Because neuroinflammatory processes are now recognized as key contributors in Alzheimer’s disease, Parkinson’s disease, multiple sclerosis and several psychiatric indications, our team can implement models allowing the evaluation of anti-inflammatory or immuno-modulatory compounds in the brain. These models can be combined with behavioral endpoints, pharmacokinetics or histological analyses to provide a full picture of the compound effect. This makes Key-Obs a relevant CRO partner for companies targeting microglia activation, cytokine pathways or blood–brain barrier alterations.

Scientific Collaboration, Publications And Partner Network

The company regularly collaborates with academic groups and industrial partners, as detailed on https://www.key-obs.com/collaboration.php and https://www.key-obs.com/partners.php. These collaborations allow sponsors to access innovative CNS models and new read-outs sooner, and to co-develop publications that strengthen their development programs. By following the updates on https://www.key-obs.com/news.php, visitors can discover recent preclinical CNS studies, posters, scientific communications and methodological improvements implemented by Key-Obs. This continuous scientific activity is a guarantee of quality, expertise and visibility for your compound.

Contacting Key-Obs For CNS Preclinical Programs

Sponsors interested in outsourcing part of their preclinical CNS research can directly contact the team through https://www.key-obs.com/contacts.php. The scientific staff will review your indication, your target, your species requirements and your timeline to design a custom preclinical protocol leveraging the existing models from the Key-Obs catalogue. Whether you are developing treatments against autism spectrum disorders, Alzheimer’s disease, ADHD, anxiety or depression, Key-Obs can propose the most relevant in vivo model and deliver a clear report that can be used in your next milestone meeting or regulatory discussion. For legal information you can also visit https://www.key-obs.com/mentions-legales.php.

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